Friday, May 18, 2012

Quercetin Decreases COMT Activity

I found this interesting tidbit of information on Dr. Ben Lynch's facebook page today.

 Quercetin is a potent inhibitor of COMT.                                
        Ouch for those with COMT mutations.
                                                                                - Dr Lynch

Huh, very very interesting. He references this study on Pubmed as his source of information.

If some of you may remember, I used to take quercetin during chelation rounds because of the hives and itchiness I used to get. It seemed to help keep me from getting hives, but as soon as I did, it was worthless.

I wonder if it was in fact doing more harm than good. You figure, while chelating, you probably don't want to slow down your methylation system any more...Nor do you want to be dumping more dopamine, NE and epinephrine into your already weakened body.

This is why I am very happy to have tested for these SNP's. It helps me to get a better understanding of what is good for my unique individual body. I still don't think it's the CAUSE of my problems, but it does help me understand why I react to the things I do and why I tend to be "different" than many people in the chronic illness community.

1 comment:

Thaimuay said...

Any finds on what helps improve COMT activity? I heard coenzyme form of B2 does... Anything else? I think I possible also react to Quercetin negatively and I also suffer from histamine issues.

What do you think about SAM-e supplementation?

Interesting to hear of any breakthroughs.